Metabolism & Pharmacokinetics

pharmacokineticsAvogadro LS provides a wide range of services related to preclinical studies for your human and veterinary drug development programs.  We offer in vivo studies in companion and farm animals, including early PK, supporting formulations screening & pharmacokinetics.

We also help our clients by providing bioequivalence, safety (residues, tolerance…), and efficacy (pharmacologically-induced models, challenge tests…) studies performed on target animal species.

Techniques :
Jugular catheterization, repeat sampling, microsampling in rodents
Bile duct cannulation in rats, mice and dogs
Surgical models can be performed on request

Development Services

Human Drug Development Services

Avogadro LS can perform various studies to faciliate human drug development, including but not limited to:

    • Pharmacokinetic
    • Bioavailability
    • Drug-drug interaction
    • PK/PD
    • Early pharmacokinetic
    • Mass balance excretion
    • Drug distribution with radiolabeled or non radiolabeled entities
    • Performance of studies in a variety of laboratory animal species

Veterinary Drug Development Services

Avogadro LS can facilitate development of veterinary drugs and biologics by offering the following services:

    • Pharmacokinetic
    • Bioavailability
    • Bioequivalence
    • Drug-drug interaction
    • PK/PD
    • Early pharmacokinetic
    • Mass balance excretion
    • Drug distribution with radiolabeled or non radiolabeled entities
    • Performance of studies in companion and food producing species